Pollen proteomics: from stress physiology to developmental priming

Pollen and Pollen Tube Proteomics

Germinated pollen grains form pollen tubes that accomplish rapid polarized growth within female gametophytic tissues in order to deliver the sperm cell to the ovule. This process is essential for successful plant fertilization in vivo. Pollen tubes are considered to be an ideal model system to study tip growth. A more comprehensive understanding of proteins involved in pollen development, germi...

Neonatal Hemodynamics: From Developmental Physiology to Comprehensive Monitoring

Maintenance of neonatal circulatory homeostasis is a real challenge, due to the complex physiology during postnatal transition and the inherent immaturity of the cardiovascular system and other relevant organs. It is known that abnormal cardiovascular function during the neonatal period is associated with increased risk of severe morbidity and mortality. Understanding the functional and structu...

Transcriptomics and Proteomics Applied to Developmental Toxicology

Developmental stress can uncouple relationships between physiology and behaviour.

Phenotypic correlations (rP) have frequently been observed between physiological and behavioural traits, and the nature of these associations has been shown to be modulated by a range of environmental stressors. Studies to date have examined the effects of acute stressors on physiology-behaviour interrelations, but the potential for permanent changes induced by exposure to stress during develop...

TRANSLATIONAL PHYSIOLOGY Challenges in translating plasma proteomics from bench to bedside: update from the NHLBI Clinical Proteomics Programs

Robert E. Gerszten, Frank Accurso, Gordon R. Bernard, Richard M. Caprioli, Eric W. Klee, George G. Klee, Iftikhar Kullo, Theresa A. Laguna, Frederick P. Roth, Marc Sabatine, Pothur Srinivas, Thomas J. Wang, and Lorraine B. Ware for the NHLBI Clinical Proteomics Programs Cardiology Division and Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Boston, Massachusetts...